Last publication from the DEEVA team!

Adaptation of the CRISPR/Cas9-based gene inactivation methodology in the amphioxus embryos. Novel and simple microinjection in fertilized eggs of the RNP complex. Efficient mutagenesis and phenotypes in F0.

Chowdhury R, Roure A and Darras S. Towards functional genetics in the European amphioxus: Efficient CRISPR/Cas9 editing reveals Ascl1/2.1 requirement for peripheral nervous system development. Developmental Biology 527, 218–225 (2025). https://doi.org/10.1016/j.ydbio.2025.08.012