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Biologie Intégrative des Organismes Marins
UMR 7232

Picophytoplankton comprise the smallest photosynthetic eukaryotes that sustain the marine ecosystems. With cell diameters smaller than 2 µm, a simple cellular organisation and compact haploid genomes, these picoalgae are excellent model organisms for studying cell metabolisms, adaptations and microbial interactions [1,2]. Not surprisingly, most natural communities of picoalgae are infected by viruses, among these prasinoviruses, very large DNA viruses that are part of the giant virus family [3,4].

Over the past 10 years, the GENOPHY team has been isolating, sequencing and studying many green picoalgae of the genera Ostreococcus [5], Micromonas and Bathycoccus [6], (class Mamiellophyceae), as well as their viruses, mostly from the Mediterranean sea, but also worldwide through our network of collaborators.

We combine experimental and bioinformatic analysis to address evolutionary and environmental genomics questions in these organisms. Our main projects are about understanding their genetic diversity, its origin and variation with biotic and abiotic factors, including anthropogenic influence [7], and the molecular basis of host-virus interactions and coevolution.

[1] Derelle et al. 2006 PNAS   PMID:16868079  
[2] Piganeau et al. 2011 Res. Microbiol.   PMID:21540104
[3] Bellec et al. 2010 Env.  Microbiol. Rep.   PMID:23766083
[4] Moreau et al. 2010 J. Virology   PMID:20861243
[5] Grimsley et al. 2010 Mol. Biol. Evol.   PMID:19734297  
[6] Moreau et al. 2012 Genome Biology   PMID:22925495       
[7] Sanchez-Ferandin et al. 2013 Appl. Env. Microbiol.   PMID:23144143

Gwenael Piganeau (gwenael.piganeau @ - 23/03/16

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    • Two phD positions available 2016 in GENOPHY group

      One phD position 2016-2019 on Genomic insights into green microalage and their interactions with viruses and bacteria is available in the GENOPHY Lab within the european ITN SINGEK training network. Eligibility criteria and Application Forms are available via the SINGEK web page.
      One phD position 2016-2019 on  Building the non-coding RNA landscape in Ostreococcus, a model marine unicellular alga...

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